TOP GUIDELINES OF PKRRATING

The activated enzyme then phosphorylates its key substrate, the translational initiation aspect eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs to some conserved spouse and children of 4 protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in response to different stimuli12, triggering the built-